Selected publications
Amherst College undergraduates are underlined.
Liimatta K, E Flaherty, G Ro, DK Nguyen, C Prado, and AE Purdy. 2018. A putative acetylation system in Vibrio cholerae modulates virulence in arthropod hosts. Applied and Environmental Microbiology. In press.
Muzhingi I, C Prado, M Sylla, FF Diehl, DK Nguyen, MM Servos, S Flores Ramos and AE Purdy. 2018. Modulation of CrbS-dependent activation of the acetate switch in Vibrio cholerae. Journal of Bacteriology. In press.
Flores Ramos S, S Nessen, A Mesfin, K Raines, S Wishloff, M Hauserman, MJ Mandel, and AE Purdy. 2018. The CrbS/R two-component system regulates the Vibrio fischeri acetate switch. In revision.
Purdy AE. 2018. “Fly models of Vibrio cholerae infection and colonization.” Methods in Molecular Biology, special edition on Vibrio cholerae. Edited by Aleksandra Sikora. Humana Press: New York, NY.
Kamareddine L, ACN Wong, AS Vanhove, S Hang, AE Purdy, K Kierek-Pearson, JM Asara, A Ali, JG Morris Jr., and PI
Watnick. 2018. Activation of Vibrio cholerae quorum sensing promotes survival of an arthropod host. Nature Microbiology. 3:243-252. doi: 10.1038/s41564-017-0065-7.
Jacob K, A Rasmussen, P Tyler, MM Servos, M Sylla, C Prado, E Daniele, JS Sharp* and AE Purdy*. 2017. Regulation of acetyl-CoA synthetase transcription by the CrbS/R two-component system is conserved in genetically diverse environmental pathogens. PLOS ONE May 2017. *Co-senior authors.
El-Bassoiny G, V Luizzi, D Nguyen, JG Stoffolano Jr. and AE Purdy. 2016. Vibrio cholerae laboratory infection of adult house fly Musca domestica. Med Vet Entomb. 30:392-402.
Hang S, AE Purdy, Z Wang, S Chang, WP Robins, JJ Mekalanos and PI Watnick. 2014. A bacterial acetate switch directs host metabolism from within the intestinal lumen. Cell Host & Microbe 16:592-604. *Highlighed in Nature Reviews Microbiology.
Wang, Z., S. Hang, A. E. Purdy, and P. I. Watnick. 2013. Mutations in the IMD pathway and Mustard counter Vibrio cholerae suppression of intestinal stem cell division in Drosophila. mBio. 4(3) e00337-13.
Purdy, A. E. and P. I. Watnick. 2011. Spatially-selective colonization of the arthropod intestine through activation of Vibrio cholerae biofilm formation. Proc. Natl. Acad. Sci. USA. 108: 19737-19742.
Purdy, A. E., D. Balch, M. L. Lizarraga-Partida, M. S. Islam, J. Martinez-Urtaza, A. Huq, R. R. Colwell, and D. H. Bartlett. 2010. Diversity and distribution of cholix toxin, a novel ADP-ribosylating factor from Vibrio cholerae. Environ. Microbiol. Rep. 2(1): 198–207.
Jorgensen*, R., A. E. Purdy*, R. Fieldhouse, M. Kimber, D. H. Bartlett, and A. R. Merrill. 2008. Cholix toxin, a novel ADP-ribosylating factor from Vibrio cholerae. J. Biol. Chem. 283: 10671-10678. *These authors contributed equally.
Case LK, L Petell, L Yurkovestkiy, A Purdy, KJ Savage and TV Golovkina. 2008. Replication of beta- and gamma- retroviruses is restricted in I/LnJ mice via the same genetic mechanism. J Virol 82:1438-1447.
Makri, S., A. E. Purdy, D. Bartlett, and J. Fierer. 2007. Pathogenicity of environmental isolates of V. cholerae in mice. Microb. Infect. 9: 1351-1358.
Purdy, A., F. Rohwer, R. Edwards, F. Azam and D. H. Bartlett. 2005. A glimpse into the genome content of the Vibrio cholerae species through identification of genes present in environmental strains. J. Bacteriol. 187: 2992-3001.
Valentine, D. L., M. Kastner, G. D. Wardlaw, X. Wang, A. Purdy, and D. H. Bartlett. 2005. Biogeochemical investigations of marine methane seeps, Hydrate Ridge, Oregon. J. Geophys. Res., 110, G02005, doi:10.1029/2005JG000025.
Case LK, A Purdy and TV Golovkina. 2005. Molecular and cellular basis for the retrovirus resistance in I/LnJ mice. J Immunology 175:7543-7549.
Purdy A, L Case, M Duvall, M Overstrom-Coleman, N Monnier, A Chervonsky and T Golovkina. 2003. Unique resistance of I/LnJ mice to a retrovirus is due to sustained IFN-g dependent production of virus-neutralizing antibodies. J Exp Med 297:233–243.
Liimatta K, E Flaherty, G Ro, DK Nguyen, C Prado, and AE Purdy. 2018. A putative acetylation system in Vibrio cholerae modulates virulence in arthropod hosts. Applied and Environmental Microbiology. In press.
Muzhingi I, C Prado, M Sylla, FF Diehl, DK Nguyen, MM Servos, S Flores Ramos and AE Purdy. 2018. Modulation of CrbS-dependent activation of the acetate switch in Vibrio cholerae. Journal of Bacteriology. In press.
Flores Ramos S, S Nessen, A Mesfin, K Raines, S Wishloff, M Hauserman, MJ Mandel, and AE Purdy. 2018. The CrbS/R two-component system regulates the Vibrio fischeri acetate switch. In revision.
Purdy AE. 2018. “Fly models of Vibrio cholerae infection and colonization.” Methods in Molecular Biology, special edition on Vibrio cholerae. Edited by Aleksandra Sikora. Humana Press: New York, NY.
Kamareddine L, ACN Wong, AS Vanhove, S Hang, AE Purdy, K Kierek-Pearson, JM Asara, A Ali, JG Morris Jr., and PI
Watnick. 2018. Activation of Vibrio cholerae quorum sensing promotes survival of an arthropod host. Nature Microbiology. 3:243-252. doi: 10.1038/s41564-017-0065-7.
Jacob K, A Rasmussen, P Tyler, MM Servos, M Sylla, C Prado, E Daniele, JS Sharp* and AE Purdy*. 2017. Regulation of acetyl-CoA synthetase transcription by the CrbS/R two-component system is conserved in genetically diverse environmental pathogens. PLOS ONE May 2017. *Co-senior authors.
El-Bassoiny G, V Luizzi, D Nguyen, JG Stoffolano Jr. and AE Purdy. 2016. Vibrio cholerae laboratory infection of adult house fly Musca domestica. Med Vet Entomb. 30:392-402.
Hang S, AE Purdy, Z Wang, S Chang, WP Robins, JJ Mekalanos and PI Watnick. 2014. A bacterial acetate switch directs host metabolism from within the intestinal lumen. Cell Host & Microbe 16:592-604. *Highlighed in Nature Reviews Microbiology.
Wang, Z., S. Hang, A. E. Purdy, and P. I. Watnick. 2013. Mutations in the IMD pathway and Mustard counter Vibrio cholerae suppression of intestinal stem cell division in Drosophila. mBio. 4(3) e00337-13.
Purdy, A. E. and P. I. Watnick. 2011. Spatially-selective colonization of the arthropod intestine through activation of Vibrio cholerae biofilm formation. Proc. Natl. Acad. Sci. USA. 108: 19737-19742.
Purdy, A. E., D. Balch, M. L. Lizarraga-Partida, M. S. Islam, J. Martinez-Urtaza, A. Huq, R. R. Colwell, and D. H. Bartlett. 2010. Diversity and distribution of cholix toxin, a novel ADP-ribosylating factor from Vibrio cholerae. Environ. Microbiol. Rep. 2(1): 198–207.
Jorgensen*, R., A. E. Purdy*, R. Fieldhouse, M. Kimber, D. H. Bartlett, and A. R. Merrill. 2008. Cholix toxin, a novel ADP-ribosylating factor from Vibrio cholerae. J. Biol. Chem. 283: 10671-10678. *These authors contributed equally.
Case LK, L Petell, L Yurkovestkiy, A Purdy, KJ Savage and TV Golovkina. 2008. Replication of beta- and gamma- retroviruses is restricted in I/LnJ mice via the same genetic mechanism. J Virol 82:1438-1447.
Makri, S., A. E. Purdy, D. Bartlett, and J. Fierer. 2007. Pathogenicity of environmental isolates of V. cholerae in mice. Microb. Infect. 9: 1351-1358.
Purdy, A., F. Rohwer, R. Edwards, F. Azam and D. H. Bartlett. 2005. A glimpse into the genome content of the Vibrio cholerae species through identification of genes present in environmental strains. J. Bacteriol. 187: 2992-3001.
Valentine, D. L., M. Kastner, G. D. Wardlaw, X. Wang, A. Purdy, and D. H. Bartlett. 2005. Biogeochemical investigations of marine methane seeps, Hydrate Ridge, Oregon. J. Geophys. Res., 110, G02005, doi:10.1029/2005JG000025.
Case LK, A Purdy and TV Golovkina. 2005. Molecular and cellular basis for the retrovirus resistance in I/LnJ mice. J Immunology 175:7543-7549.
Purdy A, L Case, M Duvall, M Overstrom-Coleman, N Monnier, A Chervonsky and T Golovkina. 2003. Unique resistance of I/LnJ mice to a retrovirus is due to sustained IFN-g dependent production of virus-neutralizing antibodies. J Exp Med 297:233–243.